The Pharmaceutical Society of Northern Ireland was established in 1925 by the Pharmacy and Poisons Act (Northern Ireland) 1925, and has been based at 73 University Street since 1933. The Society currently maintains a register of over 1800 pharmacists and over 500 premises registered within Northern Ireland.

The Society is a legal entity and, as such, has powers and duties under the Pharmacy (Northern Ireland) Order 1976.

The Council is the governing body of the Society and currently consists of 22 members of whom 18 are members of the Society; 2 represent Queens University, 1 represents the medical profession and the final member is nominated by the Pharmaceutical Wholesalers.